The NPC Platform

We use a powerful combination of Nuclear Magnetic Resonance (NMR) and Liquid Chromatography РMass Spectrometry (LC-MS) instrumentation to generate comprehensive metabolite measurements across the metabolome. Working with industry leaders Bruker Biospin and Waters Corporation, the National Phenome Centre has developed and adapted robust technologies and standard methodologies for molecular phenotyping. From lipoprotein quantification to small molecule profiling, our core suite of analytical assays provides unmatched coverage and discovery potential.

Our complementary collection of targeted analyses including both in-house methods and the Biocrates AbsoluteIDQ p150 and p180 kits for quantitative measurement of acylcarnitines, amino acids, hexoses, phospho/sphingolipids and biogenic amines provides an extensive menu of capability for collaborators looking to focus their metabolic explorations.